ATF4 Products

Antibodies
ATF4 Antibody (2B3)
ATF4 Antibody (2B3)
H00000468-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
ATF4 Antibody (739441)
ATF4 Antibody (739441)
MAB7218
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
ATF4 [p Ser245] Antibody
ATF4 [p Ser245] Antibody
NB100-81802
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
ATF4 Antibody Pair
ATF4 Antibody Pair
H00000468-AP11
Species: Hu
Applications: S-ELISA
Lysates
ATF4 Overexpression Lysate (D ...
ATF4 Overexpression Lysate (Denatu...
H00000468-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human ATF4 Protei ...
Recombinant Human ATF4 Protein
H00000468-P02
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ATF4 Protei ...
Recombinant Human ATF4 Protein
NBP1-72383
Species: Hu
Applications: PAGE
RNAi
ATF4 RNAi
ATF4 RNAi
H00000468-R02
Species: Hu
Applications: RNAi, RNAi SP
ATF4 RNAi
ATF4 RNAi
H00000468-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 468
Alternate Names
  • cAMP-dependent transcription factor ATF-4
  • Activating transcription factor 4
  • TXREB
  • TaxREB67
  • Tax-responsive enhancer element-binding protein 67
  • cyclic AMP-dependent transcription factor ATF-4
  • Cyclic AMP-responsive element-binding protein 2
  • TAXREB67CREB2cAMP response element-binding protein 2
  • CREB-2DNA-binding protein TAXREB67
  • cAMP-responsive element-binding protein 2
  • activating transcription factor 4 (tax-responsive enhancer element B67)

Research Areas for ATF4

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Phospho-Specific
Unfolded Protein Response

Bioinformatics Tool for ATF4

Discover related pathways, diseases and genes to ATF4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ATF4 Blog Posts

Check out the latest blog posts on ATF4.
The effects of ethanol consumption on glutamate production and xCT
xCT is a sodium independent glutamate transporter that regulates the exchange of extracellular l-cystine and intracellular l-glutamate across the plasma membrane. This process is critical to glutathione production and protection from subsequent ox...    Read more.
eIF2alpha - a regulator of global translation in response to cellular stress
Eukaryotic initiation factor 2 (eIF2) regulates global protein translation by binding to Met-tRNA and the 40S ribosome to form the pre-initiation complex. eIF2 is a heterotrimer consisting of alpha, beta, and gamma subunits. The 36kDA eIF2a subuni...    Read more.
CENPF Antibodies as Potential Cancer Markers
Centromere protein F (CENPF), also named mitosin, is a large human protein of 3113 amino acid residues. Its expression and localization are cell cycle-dependent. The protein levels are low in G1 phase but elevated from S to early M phase. CENPF is a n...    Read more.
Read more ATF4 related blogs.