Novus Biologicals products are now on

ATF4 Products

ATF4 Antibody
ATF4 Antibody
Species: Hu, Mu, Rt, Po
Applications: WB, ELISA
Host: Goat Polyclonal
ATF4 Antibody (SD20-92)
ATF4 Antibody (SD20-92)
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
ATF4 Antibody (2B3)
ATF4 Antibody (2B3)
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Antibody Pairs
ATF4 Antibody Pair
ATF4 Antibody Pair
Species: Hu
Applications: ELISA
Human ATF4 ELISA Kit (Colorim ...
Human ATF4 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
ATF4 293T Cell Transient Over ...
ATF4 293T Cell Transient Overexpre...
Species: Hu
Applications: WB
Recombinant Human ATF4 His-Ca ...
Recombinant Human ATF4 His-Cam Pro...
Species: Hu
Applications: PAGE


ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.


Entrez Mouse
Uniprot Human
Product By Gene ID 468
Alternate Names
  • activating transcription factor 4 (tax-responsive enhancer element B67)
  • Activating transcription factor 4
  • cAMP-dependent transcription factor ATF-4
  • cAMP-responsive element-binding protein 2
  • CREB-2DNA-binding protein TAXREB67
  • cyclic AMP-dependent transcription factor ATF-4
  • Cyclic AMP-responsive element-binding protein 2
  • TaxREB67
  • TAXREB67CREB2cAMP response element-binding protein 2
  • Tax-responsive enhancer element-binding protein 67

Research Areas for ATF4

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Unfolded Protein Response

Related ATF4 Blog Posts

Check out the latest blog posts on ATF4.
The effects of ethanol consumption on glutamate production and xCT
xCT is a sodium independent glutamate transporter that regulates the exchange of extracellular l-cystine and intracellular l-glutamate across the plasma membrane. This process is critical to glutathione production and protection from subsequent ox...    Read more.
CENPF Antibodies as Potential Cancer Markers
Centromere protein F (CENPF), also named mitosin, is a large human protein of 3113 amino acid residues. Its expression and localization are cell cycle-dependent. The protein levels are low in G1 phase but elevated from S to early M phase. CENPF is a n...    Read more.
eIF2alpha - a regulator of global translation in response to cellular stress
Eukaryotic initiation factor 2 (eIF2) regulates global protein translation by binding to Met-tRNA and the 40S ribosome to form the pre-initiation complex. eIF2 is a heterotrimer consisting of alpha, beta, and gamma subunits. The 36kDA eIF2a subuni...    Read more.
Read more ATF4 related blogs.