ASXL1 Products

Description

In Drosophila, the Additional sex combs (Asx) gene encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. Although the function of the protein encoded by this gene is not known, it does show some sequence similarity to the protein encoded by the Drosophila Asx gene. [provided by RefSeq]

Bioinformatics

Uniprot	AAH64984 Human
Product By Gene ID	171023
Alternate Names	additional sex combs like 1 (Drosophila)

Research Areas for ASXL1

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
Signal Transduction

Related ASXL1 Blog Posts

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The role of DNMT3A in development Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.

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