ARG2 Products

Description

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq]

Bioinformatics

Entrez	384 Human
Uniprot	AAH29050 Human AAH29050.1 Human NM_001172 Human NP_001163 Human P78540 Human
Product By Gene ID	384
Alternate Names	arginase 2 arginase, type II arginase-2, mitochondrial EC 3.5.3 EC 3.5.3.1 kidney arginase Kidney-type arginase L-arginine amidinohydrolase L-arginine ureahydrolase nonhepatic arginase Non-hepatic arginase Type II arginase

Research Areas for ARG2

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Lipid and Metabolism