ARA54 Products

Description

RNF14 is encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Bioinformatics

Entrez	9604 Human
Uniprot	NM_183400 Human NP_004281 Human NP_899645.1 Human Q9UBS8 Human
Product By Gene ID	9604
Alternate Names	Androgen receptor-associated protein 54 ARA54androgen receptor associated protein 54 EC 6.3.2.- HFB30E3 ubiquitin-protein ligase RNF14 ring finger protein 14FLJ26004 Triad2 protein TRIAD2

Research Areas for ARA54

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction
Zinc Finger