APEX2 Products

Antibodies
APEX2 Antibody
APEX2 Antibody
NB100-56625
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
APEX2 Antibody
APEX2 Antibody
H00027301-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Lysates
APEX2 Overexpression Lysate ( ...
APEX2 Overexpression Lysate (Native)
NBP2-07324
Applications: WB
APEX2 Overexpression Lysate ( ...
APEX2 Overexpression Lysate (Denat...
H00027301-T01
Species: Hu
Applications: WB
RNAi
APEX2 RNAi
APEX2 RNAi
H00027301-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 27301
Alternate Names
  • XTH2
  • DNA-(apurinic or apyrimidinic site) lyase 2
  • APEXL2
  • APE2
  • EC 4.2.99.18
  • EC 3.1
  • AP endonuclease 2
  • DNA-apurinic or apyrimidinic site lyase 2
  • Apurinic-apyrimidinic endonuclease 2
  • APEX nuclease 2
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2

PTMs for APEX2

Learn more about PTMs related to APEX2.

Phosphorylation
Deamination
Cleavage
Methylation

Bioinformatics Tool for APEX2

Discover related pathways, diseases and genes to APEX2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.