APCDD1 Products

Antibodies
APCDD1 Antibody
APCDD1 Antibody
H00147495-B01P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-Fr
Host: Mouse Polyclonal
Lysates
APCDD1 293T Cell Transient Ov ...
APCDD1 293T Cell Transient Overexp...
H00147495-T01
Species: Hu
Applications: WB
APCDD1 Overexpression Lysate
APCDD1 Overexpression Lysate
NBL1-07594
Species: Hu
Applications: WB
Proteins
Recombinant Mouse APCDD1 Prot ...
Recombinant Mouse APCDD1 Protein, CF
9981-AP
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human APCDD1 His- ...
Recombinant Human APCDD1 His-tag P...
10141-AP
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
APCDD1 Antibody Blocking Pept ...
APCDD1 Antibody Blocking Peptide
NB110-92756PEP
Species: Mu
Applications: AC

Description

Adenomatosis polyposis coli down-regulated 1 protein (APCDD1), also known as DRAPC1, is a negative regulator of the Wnt signaling pathway. APCDD1 acts to inhibit Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin interaction. APCDD-1 is most strongly expressed in pancreas, heart, prostate, ovary, lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. APCDD1 is expressed in both the epidermal and dermal compartments of the hair follicle, and in the dermal papilla, the matrix, and the hair shaft. Mutations in the APCDD1 gene cause hypotrichosis simplex (HTS), a rare form of non-syndromic hereditary hypotrichosis characterized by progressive hairloss in early childhood. The APCDD1 protein has also been found overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1-mutated Wilms tumors.

APCDD1 antibodies may be useful for hair loss studies and research on certian cancers.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 147495
Alternate Names
  • protein APCDD1
  • DRAPC1
  • Adenomatosis polyposis coli down-regulated 1 protein
  • B7323
  • adenomatosis polyposis coli down-regulated 1

Pathways for APCDD1

View related products by pathway and learn more about each of the pathways below.

Localization
Methylation
Osteoclast Differentiation
Axis Specification
Osteoblast Differentiation
Gliogenesis
Generation Of Neurons
Dna Methylation
Neurogenesis

Research Areas for APCDD1

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for APCDD1

Learn more about PTMs related to APCDD1.

Methylation

Bioinformatics Tool for APCDD1

Discover related pathways, diseases and genes to APCDD1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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