AMPK beta 2/PRKAB2 Products

Description

PRKAB2 is encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq]

Bioinformatics

Entrez	108097 Mouse 5565 Human 64562 Rat
Uniprot	AAH53610 Human AAKC_HUMAN Human NP_005390 Human NP_005390.1 Human O43741 Human
Product By Gene ID	5565
Alternate Names	5'-AMP-activated protein kinase, beta-2 subunit AMPK beta 2,5'-AMP-activated protein kinase subunit beta-2 AMPK beta-2 chain AMPK subunit beta-2 MGC61468 protein kinase, AMP-activated, beta 2 non-catalytic subunit

Research Areas for AMPK beta 2/PRKAB2

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Lipid and Metabolism