Species: Hu, Mu
Applications: WB
Host: Rat Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Simple Western
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
PRKAB2 is encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq]
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
5565 |
| Alternate Names |
- 5'-AMP-activated protein kinase, beta-2 subunit
- AMPK beta 2,5'-AMP-activated protein kinase subunit beta-2
- AMPK beta-2 chain
- AMPK subunit beta-2
- MGC61468
- protein kinase, AMP-activated, beta 2 non-catalytic subunit
|
Research Areas for AMPK beta 2/PRKAB2
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
![Western Blot AMPK beta 2/PRKAB2 Antibody (1092615) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab11639_human-ampk-beta-2-mab-clone-1092615-western-blot-131202595319..jpg)
![Simple Western AMPK beta 2/PRKAB2 Antibody (1092615) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab11639_human-ampk-beta-2-mab-clone-1092615-simple-western-2312202414270.jpg)
