AMPK alpha 2 Products

Description

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	5563
Alternate Names	5'-AMP-activated protein kinase catalytic subunit alpha-2 AMPK alpha 2 AMPK subunit alpha-2 AMPK2 AMPK5'-AMP-activated protein kinase, catalytic alpha-2 chain AMPK-alpha-2 chain EC 2.7.11 EC 2.7.11.1 PRKAA PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit

Research Areas for AMPK alpha 2

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
Hypoxia
MAP Kinase Signaling
mTOR Pathway
Protein Kinase
Signal Transduction
Translation Control

Related AMPK alpha 2 Blog Posts

Check out the latest blog posts on AMPK alpha 2.

AMPK Alpha 1 and lipid metabolism of adipocytes AMP-activated protein kinase (AMPK) is best known as a sensor of oxidative stress.  AMPK is activated by increased intracellular AMP levels, which are a result of alterations in cellular metabolism from causes such as hypoxia, changes in ATP, sene...    Read more.

Read more AMPK alpha 2 related blogs.