ALS2CR2 Products

Antibodies
ALS2CR2 Antibody
ALS2CR2 Antibody
NBP2-24680
Species: Hu, Bv, Ca, Eq, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
ALS2CR2 Antibody
ALS2CR2 Antibody
NB100-1181
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
ALS2CR2 Antibody
ALS2CR2 Antibody
NBP1-90183
Species: Hu, Mu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ALS2CR2 Overexpression Lysate ...
ALS2CR2 Overexpression Lysate (Nat...
NBL1-07490
Applications: WB
Proteins
ALS2CR2 Recombinant Protein
ALS2CR2 Recombinant Protein
H00055437-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
ALS2CR2 Partial Recombinant P ...
ALS2CR2 Partial Recombinant Protein
H00055437-Q01
Species: Hu
Applications: WB, ELISA, PA
ALS2CR2 Partial Recombinant P ...
ALS2CR2 Partial Recombinant Protein
H00055437-Q02
Species: Hu
Applications: WB, ELISA, PA
RNAi
ALS2CR2 RNAi
ALS2CR2 RNAi
H00055437-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

ALS2CR2 encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 55437
Alternate Names
  • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein
  • ILP-interacting protein
  • ALS2CR2candidate 2
  • CALS-21MGC102916
  • ILPIPSTRAD beta
  • Pseudokinase ALS2CR2
  • STE20-related kinase adaptor beta

Diseases related to ALS2CR2

Discover more about diseases related to ALS2CR2.

Sclerosis
Primary Lateral Sclerosis
Neurodegenerative Disorders
Nerve Degeneration
Amyotrophic Lateral Sclerosis

Research Areas for ALS2CR2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Protein Kinase
Signal Transduction

Bioinformatics Tool for ALS2CR2

Discover related pathways, diseases and genes to ALS2CR2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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