Species: Hu, Mu, Rt, Po, Bv
Applications: WB, Simple Western, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Eq
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Alpha-internexin is a Class IV intermediate filament, related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H. It is expressed only in neurons and in large amounts early in neuronal development, but is down-regulated in many neurons as development procedes. However, many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H, and some mature neurons only express the alpha-internexin subunit of neurofilament.
The very early developmental expression of alpha-internexin suggests that its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage. Therefore, alpha-internexin antibodies serve as unique probes to study and classify neuronal types and follow their processes in tissue sections and culture.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Rat
|
| Product By Gene ID |
9118 |
| Alternate Names |
- 66 kDa neurofilament protein
- alpha-Inx
- Alpha-Inx
- FLJ18662
- FLJ57501
- internexin neuronal intermediate filament protein, alpha
- MGC12702
- NEF5
- neurofilament 5 (66kD)
- Neurofilament 5
- Neurofilament-66
- neurofilament-66, tax-binding protein
- NF-66alpha-internexin
- TXBP-1
|
