Hu, Mu, Rt, Po, BvApplications:
WB, Simple Western, ICC/IF, IHC, IHC-PHost:
Hu, Mu, Rt, Po, Bv, EqApplications:
WB, ICC/IF, IHC, IPHost:
Hu, Mu, RtApplications:
WB, ICC/IF, IHC, IHC-PHost:
Applications: WB, ELISA, PA, AP
Alpha-internexin is a Class IV intermediate filament, related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H. It is expressed only in neurons and in large amounts early in neuronal development, but is down-regulated in many neurons as development procedes. However, many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H, and some mature neurons only express the alpha-internexin subunit of neurofilament.
The very early developmental expression of alpha-internexin suggests that its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage. Therefore, alpha-internexin antibodies serve as unique probes to study and classify neuronal types and follow their processes in tissue sections and culture.
|Product By Gene ID
- Neurofilament 5
- neurofilament-66, tax-binding protein
- neurofilament 5 (66kD)
- 66 kDa neurofilament protein
- internexin neuronal intermediate filament protein, alpha
Bioinformatics Tool for alpha-Internexin
Discover related pathways, diseases and genes to alpha-Internexin. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.