Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: AC
Description
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Bioinformatics
| Product By Gene ID |
158 |
| Alternate Names |
- adenylosuccinase
- adenylosuccinate lyase
- AMPS
- ASase
- ASL
- EC 4.3.2
- EC 4.3.2.2
|
Research Areas for Adenylosuccinate Lyase
Find related products by research area and learn more about each of the different research areas below.
Core ESC-Like GenesStem Cell Markers
