ADAMTS4 Products

Antibodies
ADAMTS4 Antibody (416610) [Un ...
ADAMTS4 Antibody (416610) [Unconju...
MAB4307
Species: Hu
Applications: WB, IP, ICC, Neut
Host: Mouse Monoclonal
ADAMTS4 Antibody
ADAMTS4 Antibody
NBP1-54369
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ADAMTS4 Antibody
ADAMTS4 Antibody
AF4307
Species: Hu
Applications: WB, IP
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
ADAMTS4 Antibody Pair
ADAMTS4 Antibody Pair
H00009507-PW2
Species: Hu
Applications: WB, IP
ADAMTS4 Antibody Pair
ADAMTS4 Antibody Pair
H00009507-PW1
Species: Hu
Applications: WB, IP
Kits
ADAMTS4 Colorimetric Assay Ki ...
ADAMTS4 Colorimetric Assay Kit
KA1497
Applications: Func
ADAMTS4 Colorimetric Assay Ki ...
ADAMTS4 Colorimetric Assay Kit
KA1498
Applications: Func
Lysates
ADAMTS4 Overexpression Lysate ...
ADAMTS4 Overexpression Lysate (Den...
H00009507-T01
Species: Hu
Applications: WB
ADAMTS4 Overexpression Lysate ...
ADAMTS4 Overexpression Lysate (Nat...
NBP2-07792
Applications: WB
Proteins
Recombinant Human ADAMTS4 Pro ...
Recombinant Human ADAMTS4 Protein
H00009507-Q01
Species: Hu
Applications: WB, ELISA, PA
ADAMTS4 Recombinant Protein A ...
ADAMTS4 Recombinant Protein Antigen
NBP2-56239PEP
Species: Hu
Applications: AC
ADAMTS4 Recombinant Protein A ...
ADAMTS4 Recombinant Protein Antigen
NBP2-57839PEP
Species: Hu
Applications: AC
RNAi
ADAMTS4 RNAi
ADAMTS4 RNAi
H00009507-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease. ADAMTS4 expression has been documented in normal human brain, cartilage, heart, lung, placenta, muscle, and synovium. ESTs have been isolated from human tissue libraries, including normal brain, lung, pancreas, and skeletal muscle and cancerous breast.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 9507
Alternate Names
  • ADAMTS-4
  • EC 3.4.24
  • ADAM-TS4
  • Aggrecanase-1
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 4
  • aggrecanase-1
  • ADAMTS-2
  • KIAA0688A disintegrin and metalloproteinase with thrombospondin motifs 4
  • ADMP-1EC 3.4.24.82
  • ADAM-TS 4
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4

Research Areas for ADAMTS4

Find related products by research area and learn more about each of the different research areas below.

Cancer
GPCR
Neuroscience
Vision

PTMs for ADAMTS4

Learn more about PTMs related to ADAMTS4.

Cleavage
Phosphorylation
Nitration
Sulphation
Methylation

Bioinformatics Tool for ADAMTS4

Discover related pathways, diseases and genes to ADAMTS4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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