ACSL5 Products

Antibodies
ACSL5 Antibody
ACSL5 Antibody
NBP1-59645
Species: Hu, Mu, Rt, Bv, Ca, Ze
Applications: WB, Simple Western, IHC, IHC-P
Host: Rabbit Polyclonal
ACSL5 Antibody (5H8)
ACSL5 Antibody (5H8)
H00051703-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, IP, S-ELISA
Host: Mouse Monoclonal
ACSL5 Antibody
ACSL5 Antibody
NBP2-31995
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ACSL5 Overexpression Lysate
ACSL5 Overexpression Lysate
NBL1-07266
Species: Hu
Applications: WB
Proteins
Recombinant Human ACSL5 GST ( ...
Recombinant Human ACSL5 GST (N-Ter...
H00051703-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human ACSL5 GST ( ...
Recombinant Human ACSL5 GST (N-Ter...
H00051703-P01
Species: Hu
Applications: WB, ELISA, PA, AP
ACSL5 Recombinant Protein Ant ...
ACSL5 Recombinant Protein Antigen
NBP2-52899PEP
Species: Hu
Applications: AC

Description

Long-chain-fatty-acid--CoA ligase 5, or ACSL5, is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. These proteins play an important role in both synthesis of cellular lipids and degradation via beta-oxidation. Like other isozymes of this family, ALCS5 converts free long-chain fatty acids into fatty acyl-CoA esters. Specifically, ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage.

This isozyme is highly expressed in uterus and spleen, and in trace amounts are found in normal brain. It also has significantly increased expression in malignant gliomas, where the protein functions in mediating fatty acid-induced glioma cell growth. Therefore, ALCS5 is thought to have a key role in the survival of glioma cells and may be a potential target for novel cancer treatments. Three transcript variants encoding two different isoforms have been found for this gene.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 51703
Alternate Names
  • LACS 5
  • EC 6.2.1
  • Long-chain acyl-CoA synthetase 5
  • long-chain-fatty-acid--CoA ligase 5
  • fatty-acid-Coenzyme A ligase, long-chain 5
  • long-chain fatty acid coenzyme A ligase 5
  • ACS2
  • FACL5fatty acid coenzyme A ligase 5
  • ACS5FACL5 for fatty acid coenzyme A ligase 5
  • EC 6.2.1.3
  • acyl-CoA synthetase long-chain family member 5

Research Areas for ACSL5

Find related products by research area and learn more about each of the different research areas below.

Cancer
Lipid and Metabolism

PTMs for ACSL5

Learn more about PTMs related to ACSL5.

Oxidation
Acylation

Bioinformatics Tool for ACSL5

Discover related pathways, diseases and genes to ACSL5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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