Acetyl-CoA Carboxylase alpha/ACACA Products

Antibodies
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
NB100-92012
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
MAB6898
Species: Hu, Mu
Applications: WB
Host: Mouse Monoclonal
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
AF6898
Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
Proteins
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
NBP2-38981PEP
Species: Hu
Applications: AC
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
H00000031-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
H00000031-R07
Species: Hu
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
H00000031-R06
Species: Hu
Acetyl-CoA Carboxylase alpha/ ...
Acetyl-CoA Carboxylase alpha/ACACA...
H00000031-R01
Species: Hu

Description

Acetyl-CoA carboxylase 1 (ACC1) is a biotin dependent lipogenic enzyme that is highly expressed during adipogenesis. ACC1 catalyzes acetyl-CoA carboxylation, producing malonyl-CoA, a metabolite involved in energy homeostasis regulation. Malonyl-CoA is a two carbon donor in the synthesis of long-chain fatty acids and the elongation of fatty acids found in the cystol (1). ACC1 is regulated short-term by citrate, CoA, and palmitoyl-CoA through allosteric interactions. Nutrients and hormones can be both short-term (inducing reversible phosphorylations by such as AMPK) and long-term (transcription level regulation) regulators of ACC1 (2). Highly expressed in lipogenic tissues, ACC1 is found in liver, adipose, and lactating mammary gland (3). ACC1 has been implicated as a target in the development of anti-obesity drugs (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 31
Alternate Names
  • ACC-alpha
  • EC 6.4.1.2
  • acetyl-Coenzyme A carboxylase alpha
  • ACACacetyl-CoA carboxylase 1
  • ACC1ACC
  • ACCA
  • acetyl-CoA carboxylase alpha

Research Areas for Acetyl-CoA Carboxylase alpha/ACACA

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Lipid and Metabolism
Nutrient Sensing in the Brain
Phospho-Specific

PTMs for Acetyl-CoA Carboxylase alpha/ACACA

Learn more about PTMs related to Acetyl-CoA Carboxylase alpha/ACACA.

Oxidation
Phosphorylation

Bioinformatics Tool for Acetyl-CoA Carboxylase alpha/ACACA

Discover related pathways, diseases and genes to Acetyl-CoA Carboxylase alpha/ACACA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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