5-HT6 Products

Antibodies
5-HT6 Antibody
5-HT6 Antibody
NBP1-46557
Species: Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
5-HT6 Antibody
5-HT6 Antibody
NBP2-32079
Species: Hu, Primate
Applications: IP
Host: Rabbit Polyclonal
Lysates
5-HT6 Overexpression Lysate ( ...
5-HT6 Overexpression Lysate (Native)
NBL1-11782
Applications: WB
RNAi
5-HT6 RNAi
5-HT6 RNAi
H00003362-R02
Species: Hu

Description

5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated. 5-HT6 Receptor has been reported primarily in striatum of the brain. Expression has also been seen in stomach, spinal cord, and the lymphoid tissues of rats, including peripheral blood lymphocytes, spleen, and thymus. ESTs have been isolated from brain libraries.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Product By Gene ID 3362
Alternate Names
  • Serotonin receptor 6,5-HT-6,5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine (serotonin) receptor 6,5-HT65-HT6R

Research Areas for 5-HT6

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission

PTMs for 5-HT6

Learn more about PTMs related to 5-HT6.

Methylation

Bioinformatics Tool for 5-HT6

Discover related pathways, diseases and genes to 5-HT6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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