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327-P4) chemoattracts the BaF3 mouse pro-B cell line transfected with human CCR2A in a dose dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CCL13/MCP-4 (2 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human CCL13/ MCP-4 Monoclonal Antibody (Catalog # MAB327). The ND50 is typically 10-30 µg/mL." class="big_lightbox" target="_blank">
327-P4) was serially diluted and captured by Mouse Anti-Human CCL13/MCP‑4 Monoclonal Antibody (Catalog # MAB327) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human CCL13/MCP‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF327) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
327-P4) chemoattracts the BaF3 mouse pro-B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (AR002). Chemotaxis elicited by Recombinant Human CCL13/MCP-4 (2 µg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human CCL13/MCP-4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF327). The ND50 is typically 15-40 µg/mL." class="big_lightbox" target="_blank">
327-P4) was serially diluted and captured by Mouse Anti-Human CCL13/MCP‑4 Monoclonal Antibody (Catalog # MAB327) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human CCL13/MCP‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF327) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
MCP4, also known as Chemokine (C-C Motif) Ligand 13, belongs to the intercrine beta family (small cytokine C-C) (chemokine CC). MCP4 has a role in accumulation of leukocytes during inflammation. MCP4 is known to interact with HNRNPH3, CCBP2, CCR5, CCRL1 and CCR3. MCP4 has been studied in relation to asthma, rheumatoid arthritis, lateral sclerosis, allergic rhinitis and several other diseases and disorders.