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Bestrophin 1 Products

Antibodies
Bestrophin 1 Antibody - BSA F ...
Bestrophin 1 Antibody - BSA Free
NBP2-56225
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Bestrophin 1 Antibody - BSA F ...
Bestrophin 1 Antibody - BSA Free
NBP2-92985
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Lysates
Bestrophin 1 293T Cell Transi ...
Bestrophin 1 293T Cell Transient O...
H00007439-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human Bestrophin ...
Recombinant Human Bestrophin 1 His...
NBP2-53038
Species: Hu
Applications: PAGE
Bestrophin 1 Recombinant Prot ...
Bestrophin 1 Recombinant Protein A...
NBP2-56225PEP
Species: Hu
Applications: AC

Description

BEST1 belongs to the bestrophin family of anion channels, which includes BEST2 (MIM 607335), BEST3 (MIM 607337), and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 7439
Alternate Names
  • ARB
  • Best disease
  • BEST
  • bestrophin 1
  • bestrophin-1
  • BMD
  • TU15B
  • vitelliform macular dystrophy 2
  • Vitelliform macular dystrophy protein 2
  • VMD2RP50

Research Areas for Bestrophin 1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Vision

Related Bestrophin 1 Blog Posts

Check out the latest blog posts on Bestrophin 1.
Vision Infographic: Do you see how I see?
Vision involves several parts of the eye processing light which send signals to the brain via the optic nerve to process information. Learn more about the vision process and related ocular proteins in the infographic below. Novus Biological...    Read more.
Bestrophin 1: Implications in Progressive Vision Loss
The human Bestrophin family has four members, Best1, Best2, Best3 and Best4. These transmembrane proteins can function as chloride channels, and can also regulate calcium channels (1). The Bestrophins all have a conserved domain which begins at the N-...    Read more.
"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies
Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved ...    Read more.
Read more Bestrophin 1 related blogs.