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Metabolic syndrome

Insulin signaling in adipocytes: Carbohydrate-signaling transcription factor ChREBP is the link between lipolytic enzyme Hormone-Sensitive Lipase and lipogenic enzyme ELOVL6

Inhibiting incretin GIP hormone activity in mouse and monkey models to combat obesity

The release of insulin from pancreas beta-cells is controlled by glucose levels, Vagus nerve input, and GLP-1 from the intestines.

By Jamshed Arslan, Pharm. D., PhD.

Insulin signaling in brain’s subfornical organ is crucial for regulating cardiometabolic profile

Muscle-specific UBE2O ablation requires activated AMPKα2 to protect against metabolic syndrome