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Heart Disease

Muscle-specific UBE2O ablation requires activated AMPKα2 to protect against metabolic syndrome

Clearance of elevated glucose and fatty acids by skeletal muscle is affected by the development of insulin resistance.

By Jamshed Arslan, Pharm. D., PhD.

Tags: 
Lipid and Metabolism
Heart Disease
Diabetes
metabolism
Metabolic syndrome
ampk-alpha-2
ampk-beta
ampk-gamma
UBE2O
ampk-alpha-1
acetyl-coa-carboxylase-alpha-acaca
tbc1d1
Jamshed Arslan

Metabolic Syndrome: Symptoms and associated disease states

The term, metabolism, refers to the totality of chemical reactions that occur in a biological system for the conversion of ingested nutrients into their basic constituents (i.e. proteins, lipids, nucleic acids and carbohydrates).
Tags: 
Lipid and Metabolism
Heart Disease
Diabetes
SREBP1
foxo1-fkhr
TNF-alpha
IL-6
adiponectin-acrp30
beta-3-adrenergic-r-adrb3
hormone-sensitive-lipase-hsl
glycogen-phosphorylase-muscle-form
Jamshed Arslan

We Heart HIF: HIF-1 Improves Angiogenesis Therapy in Ischemic Heart Tissue

Ischemic cardiovascular disease is the leading cause of death for both men and women in the US and most other industrialized countries. Most commonly caused by atherosclerosis of the coronary arteries, ischemic cardiovascular disease is characterized by a reduced blood supply to the heart, leading to low oxygen, glucose, and pH levels.

Tags: 
Atherosclerosis
Heart Disease
HIF-1 alpha
HIF-1 alpha antibody
Lactate Dehydrogenase A
Lactate Dehydrogenase A antibody
PDK1
PDK1 antibody