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FLK1

VEGF: Vascular endothelial growth factor

VEGF is homodimeric, disulfide-linked glycoprotein cytokine that serves as the ligand for FLT1 (VEGFR-1 receptor) and FLK1 (VEGFR-2 receptor) tyrosine kinases. It is a key modulator of physiological angiogenesis, vasculogenesis, and endothelial cell growth during basic developmental processes such as embryogenesis, skeletal growth, and reproductive functions.