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VEGFR-1

VEGF Receptors, Angiogenesis and Cancer

Vascular endothelial growth factor receptors 1 and 2 (VEGFR1 and VEGFR2) are related family members of the vascular endothelial growth factor (VEGF) family of membrane receptor tyrosine kinases. They are key regulators of physiological angiogenesis during fundamental developmental processes such as embryogenesis, skeletal growth, and reproductive functions.