RANKL lysates

Pulling RANK: Immune Response and Osteoclast Activation by RANKL

RANKL is the ligand for the receptor activator of NFkB (RANK) that belongs to the tumor necrosis factor receptor (TNFR) superfamily. RANK overexpression induces the NFkB and c-Jun-terminal kinase (JNK) downstream pathways. This pathway has been studied in detail in the bone remodeling system with regards to osteoclast activity and induction.

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NFkB

RANK

RANK antibody

RANKL

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