Blogs for May 2021

HIV-associated neurocognitive disorders involve extracellular Nef-induced modification of lipid rafts and redistribution of Alzheimer’s disease-related proteins

Friday, May 14, 2021 - 11:17
Immunohistochemical staining of paraffin-embedded ovarian cancer tissue sample with lipid-related protein Apolipoprotein E/ApoE.

Jamshed Arslan, Pharm D, PhD

Cholesterol is an essential part of animal cell membranes. Cholesterol-rich lipid rafts maintain the fluidity and protein trafficking of plasma membranes. Cellular ABCA1 protein moves cholesterol and certain fats outside of the cell. Dysregulated lipid rafts and cholesterol metabolism...


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