Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells.
Bioinformatics
| Entrez |
Mouse
Rat
|
| Product By Gene ID |
487 |
| Alternate Names |
- ATP2A
- ATP2A1
- ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
- Calcium pump 1
- Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletalmuscle isoform
- EC 3.6.3
- EC 7.2.2.10
- Endoplasmic reticulum class 1/2 Ca(2+) ATPase
- sarcoplasmic/endoplasmic reticulum calcium ATPase 1
- SERCA1 ATPase
- SERCA1
- SERCA1EC 3.6.3.8
- SR Ca(2+)-ATPase 1
|
