Species: Hu, Mu, Rt, Ca, Gp, Pm
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow, ICC/IF, Mycoplasma
Host: Rabbit Monoclonal
Species: Mu
Applications: ELISA
Description
Retinoids can reverse various premalignant lesions as well as prevent some second primary tumors. The effects of retinoids are regulated by retinoic acid receptors (RAR) and retinoid X receptors, which act as ligand-activated transcription factors. Ligand-dependent transcriptional activation of RARs is a multistep process that ends with the formation of a multimeric co-activator complex on regulated promoters (1,2). Loss of RAR-beta expression and the accumulation of p53 and Ki67 proteins may help in the early identification of esophageal cancer in high-risk populations (3).
Bioinformatics
| Product By Gene ID |
5915 |
| Alternate Names |
- beta polypeptide
- HAP
- HBV-activated protein
- NR1B2
- RAR beta
- RARB
- retinoic acid receptor, beta
- RRB2
|
