Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Description
Just as heat shock proteins function as chaperones for exposed hydrophobic patches, importins act as chaperones for exposed basic domains, and it is suggested that this represents a major and general cellular function of importins (1). RanBP9, a novel interacting protein, was localized within the centrosome throughout the cell cycle. Overexpression of RanBP9 produced multiple spots which were colocalized with gamma-tubulin and acted as ectopic microtubule nucleation sites, resulting in a reorganization of microtubule network (2). It has been shown that RanBP9 can induce GTP-Ras association and Erk phosphorylation and elevate serum response element-luciferase (SRE-LUC) expression, indicating that RanBP9 can activate the Ras-Erk-SRE pathway. Also RanBP9 stimulates Ras activation by recruiting Sos (3).
Bioinformatics
| Product By Gene ID |
10048 |
| Alternate Names |
- BPM90
- BPM-L
- RAN binding protein 9
- Ran Binding Protein in the Microtubule organizing center
- ran binding protein, centrosomal
- ran-binding protein 9
- Ran-binding protein M
- RanBP7
- RanBP9
- RanBPM
- RANBPMnovel centrosomal protein RanBPM
|
