Tetanus Toxin Antibody

Images

 
Western Blot: Tetanus Toxin Antibody [NB100-63239] - 1 ug of tetanus toxin (Sigma T3194-25UG) per well.

Product Details

Summary
Reactivity BaSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
5.0 mg/ml

Order Details

Tetanus Toxin Antibody Summary

Immunogen
Purified tetanus toxin
Localization
Secreted
Specificity
NB100-63239 detects the Tetanus Toxin which is produced by the soil micro-organism Clostridium tetani. C. tetaniinfection results in its systemic growth and secretion of tetanus, which causes muscle spasms by inhibiting neurotransmitter release. The antibody also reacts with the C-fragment of tetanus toxin.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TETX
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:500
  • ELISA 1 ug/ml
Application Notes
By WB, it detects the complete toxin (faint 150 kDa band), the heavy chain (main 100 kDa band) and the light chain (faint 50 kDa band).

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
5.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Tetanus Toxin Antibody

  • Tentoxylysin

Background

Tetanus Toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Tetanus Toxin Antibody (NB100-63239) (0)

There are no publications for Tetanus Toxin Antibody (NB100-63239).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Tetanus Toxin Antibody (NB100-63239) (0)

There are no reviews for Tetanus Toxin Antibody (NB100-63239). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Tetanus Toxin Antibody (NB100-63239) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional Tetanus Toxin Products

Bioinformatics Tool for Tetanus Toxin Antibody (NB100-63239)

Discover related pathways, diseases and genes to Tetanus Toxin Antibody (NB100-63239). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Blogs on Tetanus Toxin

There are no specific blogs for Tetanus Toxin, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Tetanus Toxin Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol TETX