TAS2R46 Antibody

Product Discontinued

TAS2R46 Antibody Summary

• Immunogen: A synthetic peptide as a part of human taste receptor, type 2, member 46 (TAS2R46, T2R46, T2R54) conjugated to immunogenic carrier protein was used as the immunogen. The antibodies generated using this antigen is expected to also recognize gene products of TAS2R43, TAS2R44, TAS2R47 and TAS2R49.
• Specificity: TAS2R46 (and also TAS2R43, TAS2R44, TAS2R47 and TAS2R49. See the Immunogen).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAS2R46
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:300

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Alternate Names for TAS2R46 Antibody

• MGC134865
• T2R54T2R46Taste receptor type 2 member 54
• taste receptor type 2 member 46
• taste receptor, type 2, member 46

Background

FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAS2R46
• Entrez:
  • 259292(Human)
• Uniprot:
  • P59540(Human)