Species: Hu, Mu, Rt, Pm
Applications: WB, IHC
Host: Rabbit Polyclonal
Description
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
259292 |
| Alternate Names |
- MGC134865
- T2R54T2R46Taste receptor type 2 member 54
- taste receptor type 2 member 46
- taste receptor, type 2, member 46
|
Research Areas for TAS2R46
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GPCR
