Serotonin Antibody (YC5/45) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity AllSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-WhMt
Clone
YC5/45
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 646

Order Details

Serotonin Antibody (YC5/45) [Janelia Fluor® 646] Summary

Immunogen
Serotonin conjugated to Bovine Serum Albumin.
Specificity
NB100-65037 recognizes serotonin and does not cross react with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin. Serotonin (also known as 5-hydroxytryptamine or 5-HT) is a biochemical messenger and neurotransmitter synthesized from L-tryptophan. Serotonin has a range of functions, including regulation of gastric motility, and may be related to some psychiatric disorders including schizophrenia and depression. Serotonin is widely distributed in the central and peripheral nervous system, and also in some non-neural tissues such as platelets.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunohistochemistry Whole-Mount
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

This antibody detects serotonin in multiple species including human, mouse, rat, and other vertebrate and invertebrate animals.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for Serotonin Antibody (NB100-65037JF646) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-65037AF350
Alexa Fluor 405 NB100-65037AF405
Alexa Fluor 488 NB100-65037AF488
Alexa Fluor 532 NB100-65037AF532
Alexa Fluor 594 NB100-65037AF594
Alexa Fluor 647 NB100-65037AF647
Alexa Fluor 700 NB100-65037AF700
Alexa Fluor 750 NB100-65037AF750
Biotin NB100-65037B
DyLight 350 NB100-65037UV
DyLight 405 NB100-65037V
DyLight 488 NB100-65037G
DyLight 550 NB100-65037R
DyLight 594 NB100-65037DL594
DyLight 650 NB100-65037C
DyLight 680 NB100-65037FR
DyLight 755 NB100-65037IR
FITC NB100-65037F
HRP NB100-65037H
Janelia Fluor 549 NB100-65037JF549
Janelia Fluor 646 NB100-65037JF646
PE NB100-65037PE

Additional Serotonin Products

Blogs on Serotonin.

How DOPA Decarboxylase Affects Neurotransmitter Synthesis
DOPA decarboxylase (DDC) is responsible for catalyzing the conversion of aromatic amino acids into their corresponding amines during the synthesis of several important neurotransmitters. Specifically, DDC catalyzes the decarboxylation of L-DOPA to...  Read full blog post.

"Freeze!" - Arrestin Antibodies Used in New Serotonin Syndrome Study
The beta-arrestin family regulate receptor binding of G-proteins, a group of seven transmembrane receptor proteins which includes the adrenergic, dopamine and serotonin receptors. Recently, arrestin antibodies were used in a study into Serotonin Syndr...  Read full blog post.

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

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