SARS Spike Protein Antibody (D005) - Chimeric

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Product Details

Summary
Reactivity V, VSpecies Glossary
Applications ELISA
Clone
D005
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated

Order Details

SARS Spike Protein Antibody (D005) - Chimeric Summary

Immunogen
Recombinant SARS-CoV Spike RBD Protein
Specificity
Has cross-reactivity in ELISA with:

SARS-CoV-2 Omicron (B.1.1.529) Spike RBD Protein
SARS-CoV-2 Omicron (B.1.1.529) Spike S1 Protein
SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein
SARS-CoV-2 Delta (B.1.617.2) Spike RBD Protein
SARS-CoV-2 Delta (B.1.617.2) Spike S1+S2 Protein
SARS-CoV Spike S1 Protein
SARS-CoV-2 Spike S1 Protein
SARS-CoV-2 Spike RBD Protein

No cross-reactivity in ELISA with:
MERS-CoV Spike S1 Protein
HCoV-HKU1 (isolate N1) Spike S1 Protein
HCoV-HKU1 (isolate N5) Spike S1 Protein
HCoV-NL63 Spike S1 Protein
HCoV-229E Spike S1 Protein
HCoV-OC43 Spike S1+S2 ECD Protein
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA

Reactivity Notes

This antibody has cross-reactivity in ELISA with:
SARS-CoV Spike S1 Protein
SARS-CoV-2 Spike S1 Protein
SARS-CoV-2 Spike RBD Protein

No cross-reactivity in ELISA with:
MERS-CoV Spike S1 Protein
HCoV-HKU1 Spike S1 Protein
HCoV-HKU1 Spike S1 Protein
HCoV-NL63 Spike S1 Protein
HCoV-229E Spike S1 Protein
HCoV-OC43 Spike S1+S2 ECD Protein

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 um filtered solution in PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

This Sars Spike Protein Antibody (D005) is a chimeric monoclonal antibody combining the constant domains of human IgG1 with mouse variable regions.

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Alternate Names for SARS Spike Protein Antibody (D005) - Chimeric

  • E2 glycoprotein
  • E2
  • Human coronavirus spike glycoprotein
  • Peplomer protein
  • S glycoprotein
  • S
  • SARS coronavirus S protein
  • SARS coronavirus Spike Protein
  • SARS CoV S glycoprotein
  • SARS CoV Spike protein
  • SARS CoV
  • SARS-CoV S protein
  • SARS-COV Spike
  • SARSCoV
  • SARS-COV-2 S protein
  • SARS-COV-2 Spike glycoprotein
  • Severe acute respiratory syndrome spike glycoprotein
  • Severe acute respiratory syndrome virus spike glycoprotein
  • Spike glycoprotein
  • Spike
  • VGL2

Background

It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients..

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for SARS Spike Protein Antibody (NBP2-90989). (Showing 1 - 2 of 2 FAQ).

  1. Do you know if Sars Spike Protein Antibody (16F1071) will cross react with SARS-2?
    • NBP2-24746 has no similarity unfortunately. However, NBP2-24808, NBP2-24942, and NB100-56578 have 100% sequence homology with the SARS-CoV-2 Spike Protein.
  2. I am looking for a primary antibody to sars spike protein to the new COVID-19.
    • NBP1-28850, NB100-56578, NBP2-24808, NBP2-24942 have 100% homology to the new SARS-CoV-2 virus.

Secondary Antibodies

 

Isotype Controls

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Research Areas for SARS Spike Protein Antibody (NBP2-90989)

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Blogs on SARS Spike Protein

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