Respiratory Syncytial Virus M2-1 Protein Antibody (5H5) - BSA Free

• Reactivity: V-Vi
• Applications: WB, ELISA, ICC/IF, IHC, IP
• Clone: 5H5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Respiratory Syncytial Virus M2-1 Protein Antibody (5H5) - BSA Free Summary

• Immunogen: hRSV strain A2 infected HeLa cells
• Specificity: This antibody has broad specificity for hRSV of both sub-groups A and B.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: Positive control(s): Human RSV A2 infected HeLa cells.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Respiratory Syncytial Virus M2-1 Protein Antibody (5H5) - BSA Free

• Fusion glycoprotein F0
• Fusion glycoprotein F1
• Fusion glycoprotein F2
• RS virus
• RSV

Background

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Respiratory Syncytial Virus M2-1 Protein Antibody (NBP2-50481)(1)

Publication using NBP2-50481

• Xie Q, Wang Z, Ni F et al. Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein PLoS ONE 2019-02-07 [PMID: 30730999] (Virus)