Profilin-like Protein Antibody

• Reactivity: Pz
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Profilin-like Protein Antibody Summary

• Immunogen: E. coli-derived recombinant T. gondii Profilin-like Protein
  Ser2-Tyr163
  Accession # AAX47289
• Specificity: Detects T. gondii Profilin-like Protein in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Reactivity Notes

T. gondii

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Profilin-like Protein Antibody

• Profilin like Protein
• Profilin-like Protein
• rPFTG

Background

T. gondii Profilin is a 163 amino acid, 18 kDa profilin-like protein that generates a potent interleukin-12 (IL-12) response in murine dendritic cells through binding to Toll‑like receptor 11 (TLR11). TLR11 does not appear to be expressed in human.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Profilin-like Protein Antibody (AF3860)(3)

Publications using AF3860

• Leroux, L-P;Chaparro, V;Plouffe, A;Johnston, B;Jaramillo, M; Toxoplasma gondii infection induces the expression of the chemokine CXCL16 in macrophages to promote chemoattraction of CXCR6+ cells Infection and immunity 2024-10-22 [PMID: 39436058] (Western Blot, Mouse)
• Diez, AF;Leroux, LP;Chagneau, S;Plouffe, A;Gold, M;Chaparro, V;Jaramillo, M; Toxoplasma gondii inhibits the expression of autophagy-related genes through AKT-dependent inactivation of the transcription factor FOXO3a mBio 2023-06-30 [PMID: 37387601] (Western Blot, Human)
• Louis-Philippe Leroux, Visnu Chaparro, Maritza Jaramillo Infection by the Protozoan Parasite Toxoplasma gondii Inhibits Host MNK1/2-eIF4E Axis to Promote Its Survival Frontiers in Cellular and Infection Microbiology 2020-09-09 [PMID: 33014898] (Western Blot, Human, Mouse)

Bioinformatics

• Uniprot:
  • AAX47289()