Polypeptide GalNac Transferase 10/GALNT10 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

Polypeptide GalNac Transferase 10/GALNT10 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 18 amino acids near the carboxy terminus of human GALNT10.

  Source: Synthetic

  (Accession #: NP_938080)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: GALNT10
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77058.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Polypeptide GalNac Transferase 10/GALNT10 Antibody Blocking Peptide

• DKFZp586H0623
• EC 2.4.1.41
• FLJ00205
• FLJ11715
• GalNAc transferase 10
• GALNACT10
• GalNAc-T10
• GALNT10
• Polypeptide GalNAc transferase 10
• polypeptide N-acetylgalactosaminyltransferase 10
• PPGALNACT10
• pp-GaNTase 10
• PPGANTASE10
• Protein-UDP acetylgalactosaminyltransferase 10
• UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
• UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 10 (GalNAc-T10)

Background

The GALNT10 gene codes for a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. The enzyme catalyzes the initial reaction in O-linked (mucin-type) oligosaccharide biosynthesis. It creates four isoforms: isoform 1: 603 AA long, nearly 69 kDA; isoform 2: 541 AA long; nearly 62 kDA; isoform 3: 366 AA long; 41 kDA; and isoform 4: 276 AA long: approximately 31 kDA. The GALNT10 gene has been studied with its contribution to thyroiditis. It interacts with genes MUC7, MUC1, GALNT1, GALNT12, and PTCH1 in the metabolism of proteins, mucin type O-glycan biosynthesis, and in post-translational protein modification.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: GALNT10