Phospho-HSP27 (S78/S82) DuoSet IC ELISA, 2 Plate

• Reactivity: Hu, Mu, Rt
• Applications: ELISA
• Conjugate: Biotin

Phospho-HSP27 (S78/S82) DuoSet IC ELISA, 2 Plate Summary

• Modification: p Ser78, p Ser82
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: HSPB1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Phospho-HSP27 (S78/S82) DuoSet IC ELISA, 2 Plate

• 28 kDa heat shock protein
• DKFZp586P1322
• Estrogen-regulated 24 kDa protein
• Heat shock 27 kDa protein
• heat shock 27kD protein 1
• heat shock 27kDa protein 1
• heat shock protein beta-1
• HMN2B
• HS.76067
• HSP25
• HSP27
• HSP27HSP 27
• HSP28CMT2F
• HSPB1
• SRP27
• Stress-responsive protein 27

Background

The heat shock proteins are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. Some HSPs are expressed at low levels under normal physiological conditions but show dramatically increased expression in response to cellular stress, others are constitutively expressed. Specific HSPs play a role in regulating apoptosis by interacting directly with key components of the apoptotic pathway.

Publications for HSP27 (DYC2314-2)(3)

Publications using DYC2314-2

• OM David, KL Lategan, MF de Cortale, EJ Pool The Stability and Anti-Angiogenic Properties of Titanium Dioxide Nanoparticles (TiO2NPs) Using Caco-2 Cells Biomolecules, 2022-09-21;12(10):. 2022-09-21 [PMID: 36291543] (Human)
• Schweiger T, Nikolowsky C, Starlinger P, Traxler D, Zimmermann M, Birner P, Hegedus B, Dome B, Bergmann M, Mildner M, Klepetko W, Hoetzenecker K, Ankersmit H Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases. PLoS ONE, 2015-03-20;10(3):e0120724. 2015-03-20 [PMID: 25793600] (Human)
• Matt P, Fu Z, Carrel T, Huso D, Dirnhofer S, Lefkovits I, Zerkowski H, Van Eyk J Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve. J. Mol. Cell. Cardiol., 2007-08-28;43(6):792-801. 2007-08-28 [PMID: 17949744] (Human)

Bioinformatics

• Gene Symbol: HSPB1