Phenytoin Antibody (1084338)

Biotinylated Phenytoin (Tocris Catalog #8862) competes with Phenytoin for binding to monoclonal mouse anti Phenytoin (MAB11680) antibody coated on a plate @ 1ug/ml in PBS. Bound biotinylated- Phenytoin was detected using Streptavidin-HRP (Catalog #DY998).

• Reactivity: All-NA
• Applications: ELISA
• Clone: 1084338
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1.0 mg/ml

Phenytoin Antibody (1084338) Summary

• Immunogen: Synthetic Hapten version of Phenytoin conjugated to KLH.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Phenytoin Antibody (1084338)

• 5,5-DIPHENYLHYDANTOIN
• 57-41-0
• Dilantin
• Diphenylan
• Diphenylhydantoin
• Epanutin
• Phenytek

Background

Phenytoin is an anticonvulsant drug which can be useful in the treatment of epilepsy. Phenytoin blocks voltage-sensitive sodium channels in neurons. This action leads to a delay in neuronal electrical recovery. Phenytoin's inhibitory effect is dependent on the voltage and frequency of neural cell firing by selectively blocking the neurons that are firing at high frequency. Phenytoin prevents the electrical spread of a focus of irritable tissue from entering normal tissue. Phenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic clonic (grand mal) seizures. Chemical formula: 5,5-diphenyl-2,4-imidazolidinedione.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.