Penicillinase Antibody [Alexa Fluor™ Plus 594]

• Reactivity: Ba
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 594

Penicillinase Antibody [Alexa Fluor™ Plus 594] Summary

• Immunogen: Penicillinase [E.cloacae] (Uniprot: P05364)
• Localization: Cytoplasmic
• Specificity: Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Penicillinase [E.clocae]. Cross reactivity against Penicillinase from other tissues and species may occur but have not been specifically determined.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Purity: Multi-step

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reactive with Penicillinase from E. cloacae.
Cross reactivity against Penicillinase from other tissues and species may occur but have not been specifically determined

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Multi-step

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Penicillinase Antibody [Alexa Fluor™ Plus 594]

• Aer 1
• Aer1
• Beta lactamase 1
• Beta lactamase AER 1
• Beta lactamase AER1
• Beta lactamase type I
• Beta lactamase
• Bla L
• Bla
• BlaL
• OXA 9
• OXA9
• Oxacillinase
• PenPC

Background

Penicillinase is a beta-lactamase, showing specificity for penicillins by hydrolysing the beta-lactam ring. Beta lactamases play a significant role in the high resistance of certain organinsms to penicillins, cephalosporins, cephamycins and carbapenems. These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties. Penicillinase resistant ß lactams have been developed, such as methicillin, although there is widespread resistance to these now also (MRSA). This antibody is useful for antibody based assays using streptavidin or avidin conjugates requiring lot-to-lot consistency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.