PCDHGA3 Antibody (S144-32) - Pan Specific

Product Discontinued

PCDHGA3 Antibody (S144-32) - Pan Specific Summary

• Immunogen: Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma-protocadherin-A3. Human: 80% identity (68/84 amino acids identical) >75% identity with other Gamma-protocadherin-A proteins
• Localization: Cell Membrane
• Specificity: Geater then 75% identity with other Gamma-protocadherin-A proteinsDetects approx 100kDa. Cross-reacts with other Gamma protocadherin-A proteins. No cross-reactivity against Gamma protocadherin-B or -C proteins.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PCDHGA3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:1000
• Application Notes: 1 ug/ml of Protocadherin Gamma A (pan) Antibody was sufficient for detection of Protocadherin Gamma A (pan) in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary Antibody.

Reactivity Notes

Based on homology, It's predicted to detect Human and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4) and 50% Glycerol
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for PCDHGA3 Antibody (S144-32) - Pan Specific

• PCDH-GAMMA-A3
• protocadherin gamma subfamily A, 3
• protocadherin gamma-A3

Background

The PCDHGA3 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked onchromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism maybe involved in their regulat

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCDHGA3