PCDHGA3 Antibody (S144-17)

Product Discontinued

PCDHGA3 Antibody (S144-17) Summary

• Immunogen: Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma- protocadherin-A3. Human: 80% identity (68/84 amino acids identical) >75% identity with other Gamma-protocadherin-A protein.
• Localization: Cell Membrane
• Specificity: Greater then 75% identity with other Gamma-protocadherin-A protein.Detects approx 100kDa. No cross-reactivity against other Protocadherin Gamma -A, -B or -C proteins.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PCDHGA3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:1000
• Application Notes: 1 ug/ml of Protocadherin Gamma A3 Antibody was sufficient for detection of Protocadherin Gamma A3 in 20 ug of COS cell lysate (transiently transfected with GFP-tagged Protocadherin Gamma A3) by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary Antibody.

Reactivity Notes

Based on homology, It's predicted to detect Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4) and 50% Glycerol
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for PCDHGA3 Antibody (S144-17)

• PCDH-GAMMA-A3
• protocadherin gamma subfamily A, 3
• protocadherin gamma-A3

Background

The PCDHGA3 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked onchromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism maybe involved in their regulat

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCDHGA3
• Uniprot:
  • Q91XY5(Human)