PCDHGA2 Antibody - BSA Free

Immunohistochemistry-Paraffin: PCDHGA2 Antibody [NBP3-41354] - DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 20ug/ml NBP3-41354; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Western Blot: PCDHGA2 Antibody [NBP3-41354] - Sample: Recombinant protein.

• Reactivity: Hu, Mu, Rt, Po
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

PCDHGA2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PCDHGA2 Antibody - BSA Free (NBP3-41354) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Human PCDHGA2 (Uniprot#: Q9Y5H1; Gly29-Phe347 (Uniprot#: Q9Y5H1)
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PCDHGA2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-20ug/mL
  • Immunohistochemistry-Paraffin 5-20ug/mL
  • Western Blot 0.2-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH7.4, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for PCDHGA2 Antibody - BSA Free

• PCDH-GAMMA-A2
• protocadherin gamma subfamily A, 2
• protocadherin gamma-A2

Background

PCDHGA2 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCDHGA2