MORF4 Antibody (OTI5F2)

Western Blot: MORF4 Antibody (5F2) [NBP2-45818] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MORF4.

Immunohistochemistry: MORF4 Antibody (5F2) [NBP2-45818] - Analysis of Adenocarcinoma of Human ovary tissue.

Western Blot: MORF4 Antibody (5F2) [NBP2-45818] - Analysis of extracts (35ug) from 9 different cell lines (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Immunohistochemistry: MORF4 Antibody (5F2) [NBP2-45818] - Analysis of Human pancreas tissue.

Immunohistochemistry: MORF4 Antibody (5F2) [NBP2-45818] - Analysis of Carcinoma of Human pancreas tissue.

Immunohistochemistry: MORF4 Antibody (5F2) [NBP2-45818] - Analysis of Carcinoma of Human thyroid tissue.

• Reactivity: Hu, Mu, Rt, Ca, Pm
• Applications: WB, IHC
• Clone: OTI5F2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

MORF4 Antibody (OTI5F2) Summary

• Description: Novus Biologicals Mouse MORF4 Antibody (OTI5F2) (NBP2-45818) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-255 of human MORF4 (NP_006783) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MORF4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin
  • Western Blot 1:2000
• Theoretical MW: 26.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for MORF4 Antibody (OTI5F2)

• CSR
• CSRB
• mortality factor 4
• SEN
• SEN1
• senescence (cellular)-related 1
• senescence-related, cellular, 1

Background

Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MORF4