MAN2A2 Antibody

Product Discontinued

MAN2A2 Antibody Summary

• Immunogen: Synthetic peptide to internal sequence of the human Mannosidase II protein.
• Specificity: Recognizes mannosidase II on the luminal side of golgi membranes. This is useful as a marker for golgi apparatus.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAN2A2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:500

Reactivity Notes

Cross-reacts with Human and Monkey. Does not cross-react with Rat. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: 0.02% Sodium Azide
• Purity: Unpurified

Alternate Names for MAN2A2 Antibody

• alpha-mannosidase 2x
• alpha-mannosidase IIx
• EC 3.2.1.114
• Man IIx
• MAN2A2
• MANA2X
• mannosidase, alpha type II-X
• mannosidase, alpha, class 2A, member 2
• mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
• manosidase, alpha-, type II, isozyme X

Background

alpha 2 Mannosidase 1A catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundantendocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling atmature synapses

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAN2A2
• Entrez:
  • 4124(Human)
  • 25478(Rat)
• Uniprot:
  • Q16706(Human)