INTS11 Antibody (RB28848)

Product Discontinued

INTS11 Antibody (RB28848) Summary

• Immunogen: This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.
• Localization: Cellular Location Nucleus. Cytoplasm.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: INTS11
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10 - 1:50
  • Western Blot 1:1000
• Theoretical MW: 67.663 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Bovine, Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.68 mg/ml
• Purity: Protein A purified

Alternate Names for INTS11 Antibody (RB28848)

• cleavage and polyadenylation specific factor 3-like
• Cleavage and polyadenylation-specific factor 3-like protein
• CPSF3-like protein
• EC 3.1.27
• EC 3.1.27.-
• FLJ20542
• INT11
• integrator complex subunit 11
• INTS11FLJ13294
• Protein related to CPSF subunits of 68 kDa
• RC68
• RC-68CPSF73L
• related to CPSF subunits 68 kDa

Background

The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: INTS11
• Uniprot:
  • Q5TA45(Human)