IgG1 Isotype Control (B-D38)

• Applications: Ctrl
• Clone: B-D38
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

IgG1 Isotype Control (B-D38) Summary

• Immunogen: Chemical molecule. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Control
• Application Notes: Isotype control for in-vivo experimentation

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS. Sterile-filtered through 0.22 um.
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Affinity purified

Alternate Names for IgG1 Isotype Control (B-D38)

• IgG1
• Igh-4
• RGD1359539
• VH7183

Background

IgG is a monomeric immunoglobulin composed of two heavy chains and two light chains. There are four subclasses of the IgG: IgG1, IgG2, IgG3 and IgG4. Each molecule has two antigen binding sites. IgG is the most abundant immunoglobulin as well as the only isotype that can pass through the placent,a thereby providing protection to the fetus in its first weeks of life before, its own immune system has developed. IgG can bind to several different kinds of pathogens, for example viruses, bacteria and fungi, and it protects the body against them by complement activation (the classic pathway), opsonization for phagocytosis and neutralization of their toxins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.