HPV18 E6 Antibody (C1P5) - Azide and BSA Free

• Reactivity: V-Vi
• Applications: WB, IHC, IP, Mycoplasma
• Clone: C1P5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

HPV18 E6 Antibody (C1P5) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse HPV18 E6 Antibody (C1P5) - Azide and BSA Free (NB100-2729) is a monoclonal antibody validated for use in IHC, WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Gel-purified HPV-18 E6-beta galactosidase fusion protein.
• Specificity: Shown to weakly react with HPV16 E6 (PMID 3033140)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Knockdown Validated
  • Western Blot 1:100-1:2000
• Application Notes: Reactive on formalin fixed tissue. Reveals a 16.5 kDa MW polypeptide in cells derived from a human cervical carcinoma.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for HPV18 E6 Antibody (C1P5) - Azide and BSA Free

• E6
• HpV18gp1
• Human papillomavirus type 18 E6
• Protein E6

Background

This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.