HPV16 E1+E4 Antibody (TVG 403) [CoraFluor™ 1]

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Product Details

Summary
Reactivity V-ViSpecies Glossary
Applications ELISA, Flow, IHC, CyTOF-ready
Clone
TVG 403
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

HPV16 E1+E4 Antibody (TVG 403) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Antigen for hybridoma production was expressed as a beta galactosidase fusion protein using an expression system and was consequently cleaved to release the E1/E4 polypeptide.
Localization
Nuclear
Specificity
The epitope recognized by this antibody survived brief fixation in 5% formaldehyde, but not prolonged fixation.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human papilloma virus

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for HPV16 E1+E4 Antibody (TVG 403) [CoraFluor™ 1]

  • ATP dependent helicase E1
  • E1
  • E4
  • HPV 16 ATP dependent helicase E1
  • HPV 16 E1
  • HPV 16 E4
  • HPV 16 replication protein E1
  • HPV16 ATP dependent helicase E1
  • HPV16 E1
  • HPV16 E4
  • HPV16 replication protein E1
  • Human papilloma virus type 16 ATP dependent helicase E1
  • Human papilloma virus type 16 E1
  • Human papilloma virus type 16 E4
  • Human papilloma virus type 16 replication protein E1
  • Human papilloma virus type 16
  • Human papillomavirus type 16 ATP dependent helicase E1
  • Human papillomavirus type 16 E1
  • Human papillomavirus type 16 E4
  • Human papillomavirus type 16 replication protein E1
  • Human papillomavirus type 16
  • Replication protein E1
  • Replication protein

Background

HPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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    Array NB100-2767CL1

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