HPi1 Antibody (HIC0-4F9) [Allophycocyanin]

• Reactivity: Hu, Mu
• Applications: Flow, ICC/IF, IHC
• Clone: HIC0-4F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

HPi1 Antibody (HIC0-4F9) [Allophycocyanin] Summary

• Immunogen: Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
• Localization: Cell surface
• Marker: Endocrine pan-islet cell Marker
• Specificity: Specific for multiple endocrine cell types.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26515645).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Tissue culture supernatant

Alternate Names for HPi1 Antibody (HIC0-4F9) [Allophycocyanin]

• human pancreatic endocrine islet cell

Background

Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al.). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.