HDDC3 Recombinant Protein Summary
A recombinant protein with a His-tag corresponding to amino acids 1 to 140 of Human HDDC3
Source: E. coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSEAAQLLE AADFAARKHR QQRRKDPEGT PYINHPIGVA RILTHEAGIT DIVVLQAALL HDTVEDTDTT LDEVELHFGA QVRRLVEEVT DDKTLPKLER KRLQVEQAPH SSPGAKLVKL ADKLYNLRDL NRCTPEVKIQ
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
Please see the vial label for concentration. If unlisted please contact technical services.
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 17.9 kDa (160aa), confirmed by MALDI-TOF
Alternate Names for HDDC3 Recombinant Protein
- EC 188.8.131.52
- guanosine-3'-5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1
- HD domain containing 3
- HD domain-containing protein 3
- Metazoan SpoT homolog 1
- metazoan SpoT homolog-1
- Penta-phosphate guanosine-3'-pyrophosphohydrolase
HDDC3, also known as guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Recombinant human HDDC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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