HBsAg Antibody (3E7)

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Immunohistochemistry-Paraffin: HBsAg Antibody (3E7) [NBP1-22568] - Human liver.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P
Clone
3E7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

HBsAg Antibody (3E7) Summary

Immunogen
Purified HBsAg subtype ayw3.
Localization
Cytoplasmic
Specificity
This reacts with the 'a' determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MBL2
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:25-1:50
Application Notes
Analyte Specific Reagent. This antibody stains the cytoplasm of antigen-positive liver cells infected with Type B viral hepatitis.
Publications
Read Publication using NBP1-22568.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
No buffer
Preservative
Sodium Azide
Purity
Tissue culture supernatant

Alternate Names for HBsAg Antibody (3E7)

  • HBsAg
  • HBV major surface antigen
  • HBV surface antigen
  • Hepatitis B Virus major surface antigen
  • Hepatitis B Virus Surface Antigen
  • Major surface antigen
  • protein S

Background

Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HBsAg Antibody (NBP1-22568)(1)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MBL2