GPR108 Antibody (1047612) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Clone: 1047612
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

GPR108 Antibody (1047612) [Alexa Fluor™ Plus 488] Summary

• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GPR108 Antibody (1047612) [Alexa Fluor™ Plus 488]

• G protein-coupled receptor 108
• GPR108
• LUSTR2
• LUSTR2Lung seven transmembrane receptor 2
• MGC14393
• protein GPR108

Background

Human GPR108, also known as Lung seven transmembrane receptor 2, is a 543 amino acids long receptor belonging to the G-protein-coupled receptors (GPCRs) family of receptors. Human GPR108 may play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response (1). I has also been shown essential function in adeno-associated virus (AAV) entry to cells (2).

1. Dong D. et al. PLoS One. 2018 Oct 17;13(10):e0205303
2. Dudek AM. et al. Mol Ther. 2020 Feb 5;28(2):367-381.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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